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306 results

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Page 1
Silk-based bioinspired structural and functional materials.
Xu Z, Gao W, Bai H. Xu Z, et al. iScience. 2022 Feb 17;25(3):103940. doi: 10.1016/j.isci.2022.103940. eCollection 2022 Mar 18. iScience. 2022. PMID: 35252822 Free PMC article. Review.
In this review, we provide an overview of the recent progress in silk-based bioinspired structural and functional materials. We first give a brief introduction of silk, covering its sources, features, extraction, and forms. We then summarize the preparation and appl …
In this review, we provide an overview of the recent progress in silk-based bioinspired structural and functional materials. We first …
Piezoresistive MXene/Silk fibroin nanocomposite hydrogel for accelerating bone regeneration by Re-establishing electrical microenvironment.
Hu ZC, Lu JQ, Zhang TW, Liang HF, Yuan H, Su DH, Ding W, Lian RX, Ge YX, Liang B, Dong J, Zhou XG, Jiang LB. Hu ZC, et al. Bioact Mater. 2022 Sep 23;22:1-17. doi: 10.1016/j.bioactmat.2022.08.025. eCollection 2023 Apr. Bioact Mater. 2022. PMID: 36203961 Free PMC article.
Herein, by simple co-incubation in aqueous suspensions at physiological temperatures, biocompatible regenerated silk fibroin (RSF) is found to assemble into nanofibrils with a beta-sheet structure on MXene nanosheets, which has been reported to inhibit the restacking and o …
Herein, by simple co-incubation in aqueous suspensions at physiological temperatures, biocompatible regenerated silk fibroin (RSF) is …
Pharmaceutical applications of silk sericin.
Shitole M, Dugam S, Tade R, Nangare S. Shitole M, et al. Ann Pharm Fr. 2020 Nov;78(6):469-486. doi: 10.1016/j.pharma.2020.06.005. Epub 2020 Jun 20. Ann Pharm Fr. 2020. PMID: 32569621 Review.
Silk sericin is an applicable protein extracted from dried silk cocoons, which are composed of a polar amino acid chain with hydroxyl, carboxyl, and amino functional groups. ...
Silk sericin is an applicable protein extracted from dried silk cocoons, which are composed of a polar amino acid chain …
Immunoregulation in Diabetic Wound Repair with a Photoenhanced Glycyrrhizic Acid Hydrogel Scaffold.
Qian Y, Zheng Y, Jin J, Wu X, Xu K, Dai M, Niu Q, Zheng H, He X, Shen J. Qian Y, et al. Adv Mater. 2022 Jul;34(29):e2200521. doi: 10.1002/adma.202200521. Epub 2022 Jun 13. Adv Mater. 2022. PMID: 35576814
This hybrid hydrogel consists of interpenetrating polymer networks composed of inorganic Zn(2+) -induced self-assembled GA and photo-crosslinked methyl acrylated silk fibroin (SF), realizing both excellent injectability and mechanical strength. ...
This hybrid hydrogel consists of interpenetrating polymer networks composed of inorganic Zn(2+) -induced self-assembled GA and photo-crossli …
Hyperglycemia modulates M1/M2 macrophage polarization via reactive oxygen species overproduction in ligature-induced periodontitis.
Zhang B, Yang Y, Yi J, Zhao Z, Ye R. Zhang B, et al. J Periodontal Res. 2021 Oct;56(5):991-1005. doi: 10.1111/jre.12912. Epub 2021 Jun 30. J Periodontal Res. 2021. PMID: 34190354
Herein, we aimed to investigate the changes of macrophage polarization in periodontitis under diabetic condition and the underlying mechanism. ...M1/M2 macrophage polarization in periodontal tissue was detected by immunohistochemistry staining. ...
Herein, we aimed to investigate the changes of macrophage polarization in periodontitis under diabetic condition and the underlying m …
Regulation of the Inevitable Water-Responsivity of Silk Fibroin Biopolymer by Polar Amino Acid Activation.
Choi W, Jun T, Lee M, Park K, Choi M, Jung S, Cha JK, Kwon JS, Jin Y, Lee S, Ryu DY, Hong J. Choi W, et al. ACS Nano. 2022 Oct 25;16(10):17274-17288. doi: 10.1021/acsnano.2c07971. Epub 2022 Sep 21. ACS Nano. 2022. PMID: 36129365
To this end, this study developed an amino acid-based technology to artificially up- or down-regulate the inevitable crystallization of silk fibroin. A case II diffusion model was constructed, and it revealed that the activity of polar amino acid is related to cryst …
To this end, this study developed an amino acid-based technology to artificially up- or down-regulate the inevitable crystallization of s …
Vascularized polypeptide hydrogel modulates macrophage polarization for wound healing.
Chen Z, Wang L, Guo C, Qiu M, Cheng L, Chen K, Qi J, Deng L, He C, Li X, Yan Y. Chen Z, et al. Acta Biomater. 2023 Jan 1;155:218-234. doi: 10.1016/j.actbio.2022.11.002. Epub 2022 Nov 15. Acta Biomater. 2023. PMID: 36396041 Free article.
Herein, we fabricate a new bioactive polypeptide hydrogel (QK-SF) constituted by silk fibroin (SF) and a vascular endothelial growth factor mimetic peptide KLTWQELYQLKYKGI (QK) for tissue regeneration by simultaneously promoting vascularization and macrophage polarizati …
Herein, we fabricate a new bioactive polypeptide hydrogel (QK-SF) constituted by silk fibroin (SF) and a vascular endothelial growth …
Regenerated silk fibroin loaded with natural additives: a sustainable approach towards health care.
Jaya Prakash N, Wang X, Kandasubramanian B. Jaya Prakash N, et al. J Biomater Sci Polym Ed. 2023 Aug;34(10):1453-1490. doi: 10.1080/09205063.2023.2170137. Epub 2023 Jan 25. J Biomater Sci Polym Ed. 2023. PMID: 36648394 Review.
It was observed that a large amount of polar functional moieties present on the silk fibroin surface enables them to compatibilize easily with the natural additives. ...Further the current status and challenges in the commercialization of silk-based biomedica …
It was observed that a large amount of polar functional moieties present on the silk fibroin surface enables them to compatibi …
Ancient fibrous biomaterials from silkworm protein fibroin and spider silk blends: Biomechanical patterns.
Johari N, Khodaei A, Samadikuchaksaraei A, Reis RL, Kundu SC, Moroni L. Johari N, et al. Acta Biomater. 2022 Nov;153:38-67. doi: 10.1016/j.actbio.2022.09.030. Epub 2022 Sep 17. Acta Biomater. 2022. PMID: 36126911 Free article. Review.
Silkworm silk protein fibroin and spider silk spidroin are known biocompatible and natural biodegradable polymers in biomedical applications. ...STATEMENT OF SIGNIFICANCE: Silkworm and spider silk proteins (silk fibroin and spidroin) are biocompatible …
Silkworm silk protein fibroin and spider silk spidroin are known biocompatible and natural biodegradable polymers in biomedica …
Porous composite hydrogels with improved MSC survival for robust epithelial sealing around implants and M2 macrophage polarization.
Li Y, Zhang J, Wang C, Jiang Z, Lai K, Wang Y, Yang G. Li Y, et al. Acta Biomater. 2023 Feb;157:108-123. doi: 10.1016/j.actbio.2022.11.029. Epub 2022 Nov 24. Acta Biomater. 2023. PMID: 36435441
Moreover, it was found that GMSCs-laden Porous GelMA/SilMA hydrogels could significantly upregulate the hemidesmosomes (HDs)-related genes and proteins expression and promote M2 polarization while inhibiting M1 polarization in vitro. Based on a rat model of early im …
Moreover, it was found that GMSCs-laden Porous GelMA/SilMA hydrogels could significantly upregulate the hemidesmosomes (HDs)-related genes a …
306 results